| 翻訳と辞書 | LisH domain 
 In molecular biology, the LisH domain (lis homology domain) is a protein domain found in a large number of eukaryotic proteins, from metazoa, fungi and plants that have a wide range of functions. The recently solved structure of the LisH domain in the N-terminal region of LIS1 depicted it as a novel dimerisation motif, and that other structural elements are likely to play an important role in dimerisation.
 The LisH domain is found in the ''Saccharomyces cerevisiae'' SIF2 protein, a component of the SET3 complex which is responsible for repressing meiotic genes In SIF2 the LisH domain has been shown to mediate dimer and tetramer formation.〔 〕 It has been shown that the LisH domain helps mediate interaction with components of the SET3 complex.〔
 ==References==
 
 
 抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』
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